Almost every dosage calculation question uses one of these five formulas. Learn them, show your work, and double-check your units.
1. Desired over have
Example: The order is amoxicillin 500 mg. You have 250 mg per 5 mL. (500 ÷ 250) × 5 mL = 10 mL.
2. Weight-based dose
Example: 10 mg/kg for a 44 lb child. 44 ÷ 2.2 = 20 kg. 10 × 20 = 200 mg.
3. IV rate in mL per hour (pump)
Example: 1,000 mL over 8 hours = 125 mL/hr.
4. Drip rate in drops per minute (gravity)
Example: 1,000 mL over 8 hours with tubing of 15 gtt/mL. (1,000 × 15) ÷ 480 = 31.25, so 31 gtt/min.
5. Weight-based drips (mcg/kg/min)
Example: Dopamine 5 mcg/kg/min for an 80 kg patient. The bag is 400 mg in 250 mL, which is 1,600 mcg/mL. (5 × 80 × 60) ÷ 1,600 = 15 mL/hr.
Tips that save points
- Convert units first (mg to mcg, lb to kg).
- Ask yourself if the answer makes sense. Ten tablets for one dose is almost always wrong.
- Follow your program's rounding rules.
Practice this in Pharmacy
35 kinds of dosage calculations, checked as you go.
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Quick answers
What is the basic dosage calculation formula?
Desired dose divided by the dose you have, times the quantity it comes in: (D ÷ H) × Q.
How do you calculate an IV drip rate in drops per minute?
Multiply the total volume in mL by the tubing drop factor, then divide by the time in minutes.
Evidence & Clinical Sources
- ISMP List of High-Alert Medications
- Vallerand & Sanoski, Davis's Drug Guide for Nurses, F.A. Davis
Reviewed against current guidelines and drug labels. Always follow your program, a current drug reference, and facility policy. Our sources policy
For learning only. Lab ranges and policies vary. Always follow your nursing program, a current drug reference, and your facility's policies.